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Regeneration of the entire human epidermis!

This is just incredible. This poor child had a rare disease that causes the skin to become weak and grow sores that are very painful. Doctors were able to use genetic therapy to basically give him a new skin. It won’t be long before there is a cure for most things that ail us. Our teeth won’t rot, our eyes won’t dim, and our minds will stay sharp until the end of our very long lives.
Skin condition

“The young patient at the center of the new study had a mutation to the gene LAMB3. To fix this, researchers took skin cells from a part of the patient’s body that was not blistering. They then cultured those cells and genetically modified them to contain a corrected copy of the LAMB3 gene. They then grafted these new skin cells onto the patient’s body. Over the course 21 months, four-fifths of the boy’s epidermis regenerated, creating a new layer of healthy skin. Testing showed that the grafted skin cells were regenerating within the patient’s body effectively.”

Doctors aren’t sure if this is a cure or not. They hold open the possibility that the disease may return. However, for now, the child has found relief and hope.

Genetic process

Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused by mutations in genes encoding the basement membrane component laminin-332. Surviving patients with JEB develop chronic wounds to the skin and mucosa, which impair their quality of life and lead to skin cancer. Here we show that autologous transgenic keratinocyte cultures regenerated an entire, fully functional epidermis on a seven-year-old child suffering from a devastating, life-threatening form of JEB. The proviral

Source: Regeneration of the entire human epidermis using transgenic stem cells | Nature

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